Intravenous Immunoglobulins: Pharmacological Aspects and Therapeutic Use
نویسندگان
چکیده
منابع مشابه
Therapeutic use of immunoglobulins.
E. Richard Stiehm, MD*, Jordan S. Orange, MD, PhD, Mark Ballow, MD, Heather Lehman, MD Division of Immunology/Allergy/Rheumatology, Mattel Children’s Hospital, UCLA School of Medicine at UCLA, CA, USA Division of Immunology, Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine, PA, USA Division of Allergy, Immunology and Pediatric Rheumatology, Women & Children’s H...
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Immunoglobulins (antibodies) are plasma proteins produced by B cells, which are essential in the defence against bacterial and viral infections. Dysregulation of the immune system can lead to the formation of autoantibodies and subsequent autoimmune disease. Therapy with immunoglobulin was first studied in the late 19th century, when Von Behring and Kitasato showed that serum taken from rabbits...
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On February 23, 1994, a U.S. Food and Drug Administration (FDA)-licensed immunoglobulin intravenous (IGIV) manufacturer initiated a worldwide withdrawal of two products following an accumulation of 14 reported cases of hepatitis in American and European patients receiving one of these products. By July 1994, this number had grown to 112 in the United States alone (5). A newly licensed version o...
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Insulin has been in use for nearly a century, but its real clinical worth has been utilized only in the last one and half decade after the landmark study on tight glycaemic control by van Den Berghe. Intravenous (i.v.) insulin is the mainstay of treatment for hyperglycaemia in many acute settings as well as in managing diabetic complications. However, i.v. insulin usage may be associated with n...
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BACKGROUND Scleromyxoedema is a variant of papular mucinosis affecting the skin and internal organs. The different therapeutic approaches proposed for scleromyxoedema are still unsatisfactory. Intravenous immunoglobulin (IVIg) has been successfully employed in the treatment of connective tissue diseases and vasculitides. PATIENTS The successful treatment of three cases of scleromyxoedema with...
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ژورنال
عنوان ژورنال: Vox Sanguinis
سال: 1986
ISSN: 0042-9007,1423-0410
DOI: 10.1111/j.1423-0410.1986.tb00202.x